Lecture 7.1 Rxns of hydroxygroups-2
Lecture'7.1'Rxns'of'hydroxyl' groups72
1.Cyclic acetal formation:5-ring vs 6-ringOHOHHO(CH2)(CH2)Sn1processCH2)OHR-+ H20(CH2)nRcyclic acetal
1.#Cyclic#acetal#forma0on:#54ring#vs#64ring#
MeOH+HOOHMeHO（HMe)Me(H+OOHMeOMeHOH+HOOHHOPhHHOHPh
2.Acetonide protection of carbohydrate hydroxyl groupsHOHOHHMeo)+oMetOMeMeO4HOOMeOMeMeoOMeHOHOOH'OHHOH+OH
2.#Acetonide#protec0on#of#carbohydrate#hydroxyl#groups#
2.1 Rxn of glucose with acetone and acidHOOHH+H+HOHOOH0HO''OHHOHOOHOHgluofuranoseglucopyranosediacetoneglucose
2.1#Rxn#of#glucose#with#acetone#and#acid#